Gene expression microarrays applied to obesity research

INNOPSYS system for quickly and efficient microarray quality control evaluation


Omic technologies arise as useful tools in obesity research1. Due to its high metabolic activity and its ability of secretion, adipose tissue is no longer considered as a passive energy keeper but as a critical component in the regulation of energy balance2. The Obesity Research Laboratory at the institute of Molecular Medecine (INSERM-Paul Sabatier University) in Toulouse (Dr. Nathalie Viguerie, Pr. Dominique Langin) uses gene expression microarrays for deciphering adipose tissue transcriptome modifications face to nutritional challenges such as low calorie diets and other clinical investigation protocols3,4


High quality microarray data is essential to allow the comparison of global expression changes in thousand of genes between different conditions. A rapid and easy quality control (QC) evaluation of microarrays was then desirable. Region Midi-Pyrenees funded the joint effort between INNOPSYS and the Obesity Research Laboratory to set up such QC.


InnoScan® microarray scanners from INNOPSYS are a line of low cost- high resolutionmicroarray scanners compatible with a wide range of both commercial and in-home made microarrays. Together with MAPIX®, a friendly image analysis software, microarray image acquisition and analysis are easily performed.


  • Adriana Lagraulet, Ph.D., INNOPSYS
  • Mohamed Rasmi, INNOPSYS
  • Cyril Cauchois, Ph.D., INNOPSYS
  • Nathalie Viguerie, Ph.D., Obesity Research Laboratory, INSERM-Paul Sabatier University, Toulouse-France


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