lifesciences
Innopsys

Differentiation of primordial germs cells from induced pluripotent stem cells of primary ovarian insufficiency

Lizhi Leng1,2, Yuequi Tan1,2, Fei Gong1,2, Liang Hu1,2,3, Wi Ouyang1,2,3, Yan Zhao3, Guangxiu Lu1,2,3, and Ge Lin1,2,3
1. Institute of Reproductive & Stem Cell Engineering , Central South University, Changsha 410078, China 2. Key Laboratory of Stem Cells and Reproductive Engineering, Ministry of Health, Changsha 410078, China 3. National Engineering and Research center of Human Stem Cell, Changsha 410078 

Abstract

STUDY QUESTION Can the induced pluripotent stem cells (iPSCs) derived from women with primary ovarian insufficiency (POI) differentiate into germ cells for potential disease modeling in vitro?

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