lifesciences
Innopsys

Polar body analysis by array comparative genomic hybridization accurately predicts aneuploidies of maternal meiotic origin in cleavage stage embryos of women of advanced maternal age

Dimitra Christopikou1, Erika Tsorva1, Konstantinos Economou1, Piran Shelley2, Setephen Davies1, Minas Mastrominas1 and Alan H. Handyside 1,2,3
1. Department of Embryogenesis, Centre for Human Reproduction, 15123 Athens, Grece
2. Bluegnome Ltd, CB21 5XE Cambridge, UK
3. Institute of Integrative and Comparative Biology, University of Leeds, LS2 9JT Leeds, UK 

Abstract

STUDY QUESTION How accurate is array comparative genomic hybridization (array CGH) analysis of the first polar body (PB1) and second polar body (PB2) in predicting aneuploidies of maternal meiotic origin in the cleavage stage embryos of women of advanced maternal age?

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