lifesciences
Innopsys

Antibody microarray typing, a novel technique for Streptococcus pneumoniae serotyping

Abstract:

The use of antibody-based miniaturized devices for microbiological applications is a field poorly investigated in the era of more developed molecular amplification techniques. A novel antibody microarray for Streptococcus pneumoniae serotyping was developed, by printing nanolitre volumes of pneumococcal serotype-specific antibodies on multi-well slides. This microarray, which showed high specificity when tested against reference and clinical S. pneumoniae isolates, can be applicable as a faster, cost-effective and accurate serotyping technique for pneumococcal epidemiological studies.

Credits:

J.M. Marimona,b, A. Monasterioc, M. Ercibengoaa, J. Pascualc, I. Prietoc, L. Simonc, E. Perez-Tralleroa,b,d

  • a. Servicio de Microbiología, Hospital Donostia, San Sebastián, Spain
  • b. Centro de Investigación Biomédica en Red Enfermedades Respiratorias CIBERES, San Sebastián, Spain
  • c. Proteomika, S.L. Parque Tecnológico de Bizkaia, Derio, Spain
  • d. Departamento de Medicina Preventiva y Salud Publica, Facultad de Medicina, Universidad del País Vasco, San Sebastián, Spain

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