InnoScan 1100

InnoScan 1110 Microarray Scanners

InnoScan 1100 Microarray Scanner  – 3-Color ultra-high resolution scanner

Multiplexed whole-slide imaging

InnoScan 1100 Microarray Scanner

0.5μm pixel size, equivalent to 20x microscope magnification
High sensitivity : high performance analogical PMTs
3-color simultaneous confocal detection

Easy automation

Real-time autofocus or in-content focus system
24-slide autoloader for high-throughput applications
Automated image acquisition with Mapix software

Reliable and traceable results

Barcode reader
Accurate control of acquired images
InnoScan 1100 Microarray Scanner supplied with a validation slide which verifies scanner performance

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Brochure

Technology

Microarray scanners laser confocal

Confocal detection

  • Optimize fluorescence detection
  • Assure good focalization all along the scan
  • Less background
  • SNR is increased by 2.5 times
Microarray scanners laser autofocus

Real-time autofocus

  • Detection idone through a spatial phinhole
  • Follows the slide movement and deformation in real time during the scan
  • Avoid all out-of-focus signal
Microarray scanners laser barcode

Automatic barcode reader

  • Reliable and traceable results
Microarray scanners laser slides

All standard microscope slides format

  • Glass
  • Nitrocelluose coated glass
  • Plastic
  • Silicon wafer
  • Gold coated glass
Microarray scanners dynamic range

Dynamic range

  • From > 104 to >106
  • Detect the lowest signals avoiding saturation.

Technical specifications

InnoScan 1100

PIXEL SIZE0.5 - 40μm
LASER EXCITATION WAVELENGTH488nm532nm635nm
COMPATIBLE FLUOROPHORES*Cy2, FITC
Alexa Fluor 458, Alexa Fluor 488		Cy3
Alexa Fluor 544, Alexa Fluor 555		Cy5, DRAQ 5 Alexa Fluor 647
LASER POWERAdjustable (2 laser powers)
LOADER CAPACITY1 slide
DETECTION TYPEReal-time confocal with 3 analog photomultipliers (PMT)
PMT GAINAdjustable from 0 to 100%
(Linear from 1 to 100%)
OPTICAL FILTER7 position filter wheel**
1 standard fluorescence and 1 neutral density filter per channel;5 additional filters on request
FOCUSReal-time autofocus
Manual focus: offset adjustment 300 μm range, 1 μm increment
SLIDE SIZECompatible with all standard microscope slides: 25-26 x 75-76 mm2 / 1” x 3” ; thickness: 0.9 - 1.2 mm
SCANNING AREAAdjustable up to 22 x 74 mm2
SCANNING SPEEDFrom 10 to 35 lines/second (l/s)
3.6 minutes per slide at 10 μm and 10.5min for an area 22x22 mm2 at 1μm
DYNAMIC RANGE> 104 in normal mode or > 106 in dynamic extension mode
UNIFORMITY> 95%
BARCODE READERAutomatic barcode reading
INTERFACEEthernet interface
IMAGE FORMATTIFF (16-bit and 20-bit in dynamic extension mode)
POWER SUPPLY~ 100-240 VAC, 1.2 A, 50-60 Hz
ACQUISITION SOFTWAREMAPIX (image acquisition and spot quantification software)
DIMENSIONS (LXDXH)316 x 549 x 432 mm3 12.5” x 21.6” x 17.0”
WEIGHT30 kg (66.1 lbs)

InnoScan 1100 AL

LOADER CAPACITY24 slides
DIMENSIONS (LXDXH)322 x 656 x 439 mm3 - 12.7” x 25.8” x 17.3”
WEIGHT35 kg (77.1 lbs)

* Non exhaustive list, please contact us for more information about fluorophore compatibility
Please contact us for any additional information.

Class I laser product for research use only
Specifications subject to change without notice
Contact us for the most recent specifications

Applications Notes

How are the InnoScan microarray readers being use to combat infectious diseases

Magnetic-microcontact printing based ECM nano-patterning allows homogeneous controlling of cell growth and behavior – InnoScan 1100 Microarray Scanner

High Throughput Cell Microarray Scanning with the InnoScan 1100 AL microarray reader

InnoScan Microarray Scanners Applications in Glycobiology

Publications

  • 2020
  • Czech Republic

Gregor T, et al. Elucidation of protein interactions necessary for the maintenance of the BCR–ABL signaling complex. Cell. Mol. Life Sci. 2020; 77: 3885-3903

  • 2020
  • Slovenia

Novak M, et al. Binding specificity of ostrolysin A6 towards SF9 insect cell lipids. Biochim Biophys Acta Biomembr. 2020; 1862(9):183307

  • 2020
  • USA

Kupai A, et al. A degenerate peptide library approach to reveal sequence determinants of methyllysine-driven protein interactions. Front Cell Dev Biol. 2020; 8: 241

  • 2020
  • USA

Rajan A, et al. Enteroaggregative E. coli adherence to human heparan sulfate proteoglycans drives segment and host specific responses to infection. PLoS Pathog. 2020; 16(9): e1008851

  • 2020
  • USA

Kappler K, et al. Limited neonatal carbohydrate-specific antibody repertoire consecutive to partial prenatal transfer of maternal antibodies. Front. Immunol. 2020; 11: 543629

  • 2020
  • USA

Jordan D, et al. Three-color imaging enables simultaneous screening of multiple RNA targets on small molecule microrrays. Curr Protoc Chem Biol; 2020; 12(4): e87

Applications

Glycomics
The biological importance of glycans in several cell functions range from cell-matrix interactions to organ structure support and from pathogen-host interaction to organism immune regulation.
Infectiology
Viruses, bacteria and parasites can cause deleterious diseases requiring rapid and efficient detection and therapeutic tools. Emerging infectious diseases with little known mechanisms of infection and pathogenicity represent a big challenge for research and clinics. 
Protein arrays
Proteins are considered to be the key effectors of cellular response to external stimuli. Differential expression of key proteins can modulate cell fate, either cell differentiation, proliferation or death. Protein microarrays are a powerful tool for high-throughput screening

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