Checking immunofluorescence staining specificity with InnoQuant scanner for studying the display of sialic acid in large ferret lung tissue sections
Aadvancements in imaging technology have introduced slide scanners, which allow users to image multiple samples in a single session with minimal user input, enabling more efficient project scaling.
Using Cell Microarray (CMAs) it is possible to study the interactions and behaviors of cells face to different stimuli. CMAs can be created by spotting different cell binding molecules such as extracellular matrix proteins.
Protein detection by fluorescence-labelled antibodies on tissue sections is a widely used technique for the biomarker screening in complex diseases such as cancer to define biomarker expression on tumor cells and its distribution on a defined tissue.
In the field of cancer research, many advancements have been made over the last decade through studies of the tumor microenvironment. Tumor sample tissues are characterised by a significant spatial heterogeneity associated with biological complexity.
Plants are ideal organisms in the studying of cell functions and organization. In comparison to an animal model, plants are easy to growth and manipulate.
Fluorescence immunostaining techniques on cultured cells or individual cells help to follow the protein expression and activity changes by targeting specific antigens with fluorescence-labelled antibodies.
Protein detection by fluorescence-labelled antibodies on tissue sections is a widely used technique for the biomarker screening in complex diseases such as cancer to define biomarker expression on tumor cells and its distribution on a defined tissue.
Using fluorescence-labelled antibodies against specific antigens make it possible to highlight the presence of a molecule of interest directly within a tissue section.
Reverse Phase Protein Arrays (RPPA), also named cell lysate arrays, have been shown to be a useful tool for biomarker evaluation in large patient cohorts.
Genes are transcribed into messenger RNAs which represent the dynamic and biologic state of a cell at a given time. Using DNA microarrays, it is possible to identify mRNAs present in a sample and quantify their levels
Protein arrays are widely used in labs in order to study protein functions and interactions involved in different cell processes. For example, kinase arrays allow the study of the activity of protein kinase.
Array CGH (aCGH) analysis to determine chromosomal Copy Number Variation (CNV) is nowadays a routine laboratory technique on cytogenetics research and diagnostics.
Proteins are considered to be the key effectors of cellular response to external stimuli. Differential expression of key proteins can modulate cell fate, either cell differentiation, proliferation or death. Protein microarrays are a powerful tool for high-throughput screening
